Research

Cells are living and dynamic systems with complex responses to stimuli. We are pioneering advanced label-free imaging tools to study biophysical interaction at the cellular level, including movement of water across the cell membrane, and mapping cytoskeletal structure to function.

Many label-free imaging modalities acquire vital but limited biological information.  We are exploring ways to combine quantitative phase imaging, Raman spectroscopy, and Brillouin spectroscopy for multimodal, label-free characterization of cell health.

Proper characterization of wounds is critical to deliver tailored treatment. We are developing technologies for burn wound imaging using optical coherence tomography.

Many biological processes occur within sub-millisecond timeframes. We are developing imaging tools to characterize biological responses to stimuli at high frame rates. Applications include studying mechanisms of laser eye injury and pulsed ablation of tissues.

Design is a critical aspect of our work.  We have developed imaging systems for extreme environments (high-power radiofrequency exposure, simulated microgravity), accounting for optical, mechanical, and thermal performance.